When trying to lose weight with semaglutid the goal is the least amount of nausea with the most amount of weight loss. I start patients at 0.25mg or 5 units on an insulin syringe. Each week patients increase their dosing by 0.25mg or 5 units until they are losing 2-5# weekly. Once a patient hits a dosing where they are losing 2# weekly, I recommend staying at this dosing until weight has plateaued for two weeks. At this point, moving up by 5 units or 0.25mg would be prudent to continue the weight loss. If nausea occurs for more than 1 day at any dosing, use a slightly lower dose the following week. For example, if week 3 at 0.75mg or 15 units made you nauseous for 2 days, bump down to 13 units or 0.65mg. If nausea does occur, use ginger as much as possible to lower this nausea.
DOSING of H Growth Hormon:
For anti-aging, general health & healing, fat mobilization
For these purposes, a dose of 2-3 IU’s per day will be sufficient for the majority. A dose of 1.5 to 2.0 IU’s is considered to be a full replacement dose for those in their middle-age and beyond.
For gaining lean muscle and substantially improving body composition
For this purpose a dose of 4-8 IU’s per day will be necessary. Most people will respond very well at a dose of 4-5 IU's per day.
For maximum benefit in this regard, the addition of Insulin, and low-dose T3 would be something to seriously consider. More on this in our comparative cycle guide of H GH/Insulin/IGF-1.
Regardless of your goal, as a general rule the best way to begin your H GH program is to start with a low dose and ease your body into the higher doses. This will allow you to avoid or at least minimize many of the more common sides of H GH such as bloating and joint pain & swelling. Most people can tolerate up to approximately 2 IU’s with few sides, so that would be a good place to start.
For many using this as a general supplement, that is as high as you will need to go. For others this will be only the start. Above 2.5 – 3 IU’s, I would definitely suggest that your split your injections into two per day instead of one unless it is just not feasible to do so.
Here is what a good ramp up program would look like:
Weeks 1-4 = H GH 2 IU’s one injection
Week 5 = H GH 2.5 IU’s one injection
Week 6 = H GH 3.0 IU’s split into two injections of 1.5 IU’s each
Week 7 = H GH 3.5 IU’s split into two injections of 1.75 IU’s each
And so forth until you reach your desired dose.
If at any point in this progression you begin to have unbearable bloating or joint pain, drop the dose by 25% and hold it at this lower dosage for a couple of weeks. If the sides subside, begin your progression back up toward your desired level. If the sides remain, lower your dose again and hold it at the lower level for two weeks before beginning the upward progression. This method will keep your H GH experience a good one and side free for the most part.
For a normal cycle of 5-8 months in length, injecting once or twice a day, 7 days a week should be fine. While there are studies that suggest that the suppression from exogenous H GH is short lived (about 4 hours from injection), there are no large-scale studies to indicate safety of everyday injections in long-term use. There are studies by anti-aging groups demonstrating that a day or two off per week is adequate to protect the pituitary and its triggers over long cycles. If your use of H GH becomes more a lifestyle than a single cycle, I would consider running it 5 on/2 off, or 6 on/ 1 off until such time as we have reliable data demonstrating long-term safety sans any degradation of your own output or the triggers initiating that output.
Another option would be to run your H GH cycle everyday for the first two months to get your IGF-1 levels elevated quickly and to a level to assist you in an anabolic way, then drop back to 5 days a week.
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